Magnesium L-threonate in Brain Fog and Fibromyalgia Pain

Magnesium L-threonate in Brain Fog and Fibromyalgia Pain

As we age, it's common for cognitive function to experience a gradual decline. This decline can also be seen in conditions like Alzheimer's disease. Interestingly, animal studies have shown that increasing the brain's magnesium levels can enhance the number and function of synapses, the connections between brain cells, making animals smarter and more mentally agile.

However, most oral magnesium supplements struggle to pass through the blood-brain barrier and reach the brain. That's where MMFS-01, a revolutionary form of magnesium threonate, comes into play. Developed by a team from MIT, this form of magnesium has the unique ability to cross the blood-brain barrier, making it a potential game-changer for cognitive health.

The Study Unveiled

A significant study conducted by Neurocentria's team has shed light on the impressive potential of MMFS-01 in improving mild cognitive function in aging humans. In just six weeks, participants showed substantial improvements in overall cognitive function, which continued throughout the 12-week study. On the other hand, those receiving a placebo did not experience similar enhancements.

The study involved 50 to 70-year-old volunteers, all displaying mild cognitive impairment. They were divided into two groups, with one group taking MMFS-01 and the other a placebo. Various cognitive tests were performed before and after the treatment period, measuring executive function, working memory, attention, and episodic memory.

The Findings

The results were intriguing. While executive function significantly improved with MMFS-01 at both 6 and 12 weeks, working memory showed significant improvement only at six weeks, with the placebo group catching up at 12 weeks. Attention improved with MMFS-01 compared to baseline, but this difference wasn't statistically significant compared to the placebo group. Episodic memory, too, improved with MMFS-01 at week 12, but not significantly better than the placebo.

However, when overall cognitive ability was calculated by combining results from all four tests, the MMFS-01 group scored significantly higher than the placebo group. This improvement was evident at both week 6 and week 12. Intriguingly, those receiving MMFS-01 with the greatest increase in red blood cell magnesium levels were more likely to experience substantial cognitive improvement. Notably, there were no major side effects observed during the study.

The Potential for Fibromyalgia Pain Relief

Separate research suggests that magnesium may also offer benefits for fibromyalgia pain. This could be due to magnesium's ability to inhibit the activity of NMDA receptors, believed to contribute to fibromyalgia pain. An open-label study at Mayo Clinic found that transdermal magnesium chloride spray reduced fibromyalgia pain when used twice daily for three weeks.

Should You Consider Magnesium Threonate?

Considering the potential benefits for brain fog and cognitive function in fibromyalgia and chronic fatigue  it may be worth exploring magnesium threonate as a treatment option. However, it's essential to work with your doctor, especially if you have kidney dysfunction. Monitoring red blood cell magnesium levels during treatment can also be beneficial.

While we await more research funding, individual experiences can help inform others. So, if you decide to try magnesium threonate, sharing your experience can contribute to a collective understanding of its effectiveness. Let's work together to uncover the potential of this new form of magnesium and its role in enhancing cognitive health and combating brain fog.

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